Consider the following characteristic growth curve for chond…

Consider the following characteristic growth curve for chondrocytes in vitro as well as the diagram for a tissue-engineered cartilage construct. It is generally thought that chondrocytes can undergo only a 10-fold expansion in ex vivo culture. Given this information, what is the minimal number of chondrocytes required to grow the graft pictured at a final density of 1 X 106 cells/cm3? Calculate the amount of time that it would take to end with the final therapeutic cell number, given your starting population of cells.