Anti-K was detected in a patient’s serum 1 year ago in a routine antibody screen. This patient was transfused red cells containing antigen specific for anti-K. Forty-eight hours later the patient began exhibiting signs of a hemolytic anemia. What type of transfusion reaction is present?

ADVANCED CONCEPTS A patient who usually takes metformin was switched to insulin immediately following an angiogram. Which patient finding indicates it is safe for the patient to switch back to metformin?

Although sickle cell trait is usually asymptomatic, sickling can still occur when caused by which of the following?

The morphologic hallmark of HS hereditary spherocytosis on the peripheral blood smear is:

Where does extravascular phagocytosis of red cells occur?

A 5-year-old boy presents with a hemoglobin and hematocrit of 10 g/dL and 30% respectively, a serum bilirubin of 3.0 mg/dL, a RBC count of 4.0 million/µL, and splenomegaly. Which clinical expression of thalassemia best correlates with the data?

ADVANCED CONCEPTS A patient taking tamsulosin (Flomax) asks how the drug works. What is your best response?

ADVANCED CONCEPTSA patient is prescribed the testosterone patch 4 mg/day applied to the upper body once daily at night. Which side effects will you teach the patient may occur?

Intravascular hemolysis due to mechanical etiologies is usually accompanied by the presence of __________ on the peripheral blood smear.

Which of the following therapies represents the “mainstay” of treatment for painful crises to correct fluid and electrolyte deficits in patients with sickle cell anemia?