In humans and mice, the antibody constant (C) heavy chain gene segments are in which order?

Recombination of immunoglobulin gene segments serves to

What is central tolerance?

How do natural killer cells recognize tumor infected cells?

Describe the 6 antibody-mediated effector functions discussed: (at least a sentence for each) a.  neutralization b. opsonization c.  agglutination d. complement fixation e. antibody-dependent cell-mediated cytotoxicity f.  degranulation

When talking about preventing autoimmunity, what is central tolerance?

Class I MHC are expressed by __________________________ cells, whereas Class II MHC are only expressed by ____________________ cells.

When talking about vaccines, what does “attenuated” mean?

Antigen presentation on the MHC – the exogenous pathway.  Is the antigen presented on MHC 1 or II?   Is the antigen presented to Tc cells or TH cells?

What are the basic steps of leukocyte extravasation?