Two weeks after undergoing surgical closure of an atrial sep…

Two weeks after undergoing surgical closure of an atrial septal defect, a 2 year old male presents with several days of irritability and anorexia. On physical exam, he is pale and mildly tachypneic. His pulses are weak and irregular. The auscultated heart rate is regular at 160 bpm. The most likely diagnosis is:

A couple comes to you with questions following the diagnosis…

A couple comes to you with questions following the diagnosis of Trisomy 21 in their now 18 week fetus. They ask what medical problems may be anticipated for a child who has Down syndrome. Of the following, the medical problem that is encountered most frequently in infants who have Trisomy 21 is

A 16-year-old boy is referred to with a history of malaise a…

A 16-year-old boy is referred to with a history of malaise and fatigue. He has not been sleeping well and complains of cough and nighttime sweating. On examination, you note some enlarged nontender lymph nodes in the posterior cervical chain, as well as a large supraclavicular node. Review of his growth chart shows a 12% weight loss from his annual visit only a few months ago. A chest x-ray shows an anterior mediastinal mass and hilar adenopathy. Which of the following is the most likely diagnosis?

A 5 month old infant recently adopted from Southeast Asia pr…

A 5 month old infant recently adopted from Southeast Asia presents to the Emergency Department with pallor, failure to thrive, frontal bossing, hepatomegaly, splenomegaly, and jaundice. In considering differential diagnoses, the most helpful diagnostic study results to indicate Beta Thalassemia would be: