Place the following phases of Investigational New Drug (IND)…

Place the following phases of Investigational New Drug (IND) approval in the correct order: 1. The drug is investigated as a treatment for a small number of individuals with the disease the drug is intended to treat. 2. The drug is investigated in large, multicenter studies to establish efficacy and safety. 3. The drug is investigated in small groups of healthy volunteers to establish its activity.