A 22-year-old pregnant woman presents with urinary problems….

A 22-year-old pregnant woman presents with urinary problems. You diagnose her as having a urinary tract infection. You want to provide her with a course of antibiotics that will successfully treat her infection, but you also need to ensure that her fetus’ health will not be jeopardized by the treatment. Which trimester of pregnancy is the potential risk to the fetus the greatest upon exposure to medications?

A 68-year-old male with a history of chronic heart failure p…

A 68-year-old male with a history of chronic heart failure presents to the clinic with worsening shortness of breath and peripheral edema. On examination, his blood pressure is 140/85 mmHg, and he has bilateral pitting edema up to the knees. His heart rate is 88 beats per minute, and lung auscultation reveals crackles at the bases. Laboratory tests show elevated Btype natriuretic peptide (BNP) levels. Which of the following is the most appropriate initial pharmacologic treatment for this patient’s fluid retention?