The muscle enzyme hexokinase catalyzes the phosphorylation of glucose, where image014601c63e5.gif = 0.05 mM with respect to glucose. Select the effect on image015601c63e5.gif  of the hexokinase-catalyzed reaction when glucose concentration increases from 5 mM to 10 mM.

How the content of t changes after the following assignment? >>> t = (1,2,3,10) >>> t = 100

Given the vo vs. S plots below for an enzyme in the presence or absence of a competitive inhibitor, Enter True or False for each of the following statements. CompetitiveInhibition.png ​Prompt ​Response ​The K M a p p of the inhibited enzyme is larger than the KM of the uninhibited enzyme because the KM of the inhibited enzyme has changed. ​ ​Addition of more inhibitor will not change the K M a p p of the inhibited enzyme. ​ ​The vo at saturating substrate concentration will be the same for the inhibited and uninhibited reaction. ​ ​Using one-half the concentration of inhibitor will increase the vo at saturating substrate concentration. ​

Select the characteristic that is common to the structures of α-helices and β-sheets.

Cysteine’s side chain thiol is ionizable, where image005601c63e5.gif  and the R represents the rest of the amino acid molecule. Given the pH titration curve of the Cys side chain determine its ionization state at physiological pH (7.4).CyspKa.png

The image below is a stick rendering of an α-helix looking end-on from its N-terminus. What occupies the interior space of the helix center (arrow) in proteins? AlphaHelix_N_color.png      

Identify the amino acid that will have a net charge of +1 at pH 7.

Click on the oxygen atom of the depicted dipeptide that is incorrectly displayed at physiological pH (pH 7.4).

The side chain of which amino acid below is most likely to be buried in the hydrophobic core of a protein? HSLKP.png 

Given the progress curve below for the uncatalyzed reaction L-Pro ↔ D-Pro, identify the correct response to each prompt. AxSA6c.png