At preschool, 4-year-old Maverick rarely joins his peers in play. Instead, he tends to carefully observe his classmates as they transition from one play center to the next. According to Mildred Parten, Maverick is engaged in _____ play.

At preschool, 4-year-old Maverick rarely joins his peers in play. Instead, he tends to carefully observe his classmates as they transition from one play center to the next. According to Mildred Parten, Maverick is engaged in _____ play.

Phosphorylation of which protein(s)’s C-terminal domain tail serves as the timer and spatial organizer of eukaryotic transcription?

The mediator complex components differ between organisms but otherwise stay the same in each cell type

You have identified a new Sigma factor that can bind directly (with varying affinities) to DNA regions that have the sequences shown below. Based on these results, what is the strongest promoter sequence?  

You are fascinated by the biochemical pathway that leads to the biosynthesis of the amino acid Arginine that we learned about in the Beadle Tatum experiment. You mutagenized E. coli, and identified an Arginine auxotroph in which the mutation maps to Gene 3 encoding the Enzyme 3 that converts Citrulline to Arginine. You find the Gene 3 mutation resulted in a deletion of an inverted repeat sequence occurring 5′ (upstream) to a GT-rich sequence at the 3′ end of the gene.  Further examination shows that the gene is able to be transcribed but no protein is made (hence it being an auxotroph for Arginine). Based on these data, your most likely prediction would be:

In the “Christmas Tree diagram of rRNA transcription, which of strands represents the coding strand?

You are studying a yeast mutant where the CTD tail of RNA Pol II has several key serines (phosphorylatable amino acids) converted to alanines (non-phosphorylatable). The result of these changes is the failure of polyA polymerase (PAP) to bind during transcription. The resulting RNA polymerase protein would most likely  be capable of synthesizing:

You are fascinated by the biochemical pathway that leads to the biosynthesis of the amino acid Arginine that we learned about in the Beadle Tatum experiment. You mutagenized E. coli, and identified an Arginine auxotroph in which the mutation maps to Gene 3 encoding the Enzyme 3 that converts Citrulline to Arginine. You find the Gene 3 mutation resulted in a deletion of an inverted repeat sequence occurring 5′ (upstream) to a GT-rich sequence at the 3′ end of the gene.  Further examination shows that the gene is able to be transcribed but no protein is made (hence it being an auxotroph for Arginine). Based on these data, your most likely prediction would be:

The mediator complex components differ between organisms but otherwise stay the same in each cell type