Enzymes are [not_consumed] by the reaction they catalyze.  H…

Enzymes are by the reaction they catalyze.  Heat and pH changes may killing its activity. Enzyme inhibitors can also interfere with activity. For instance, the antibiotic Trimethoprim exerts its effect on bacteria by being a folic acid . Folic acid is important for cell process such as synthesis, repair, and methylation of DNA. When administered to a patient with a bacterial infection, Trimethoprim will enter the bacterial cell and block the enzyme intended for folic acid. This interference is called . Trimethoprim prevents the normal metabolic process in the bacteria with an outcome of cellular death.