BB is a 55 yo male who presents to the clinic with complaints of failure to maintain an erection. He is evaluated for cardiovascular risk and found to be in general good health. He is prescribed Tadalafil (Cialis) for treatment. What is the mechanism of action of tadalafil? Decreasing the degradation of cyclic GMP via phosphodiesterase inhibition, which increases the relaxation of cavernosal smooth muscle and cavernosal arterial blood flow is the mechanism of action for which of the following treatments for erectile dysfunction: 

The study of drug movement through the body is known as:

A 24 year old male has an eight-month history of loose thought associations, social withdrawal, auditory hallucinations, and deterioration in his personal appearance and hygiene. Upon examination, he is noted to have a flat affect, perceptual distortions, and behaves like he is detached from his own actions. If chose for treatment, which of the following medications would require weekly WBC monitoring for the first six months?

This anticoagulant agent acts in several sites of the coagulation cascade, with its principle action being inhibition of factor Xa and can be reversed with protamine. Which anticoagulant has this mechanism?

Sacubitril/valsartan has class I level of evidence justifying its use as an agent that is GDMT (Guideline directed medical therapy.) What mechanism of action provides its effects?

A 26 yo male in your care has been diagnosed with major depression syndrome. You wish to start him on pharmacologic therapy, but he expresses significant concern regarding sexual side effects. Which of the following depression medications is an option that will reduce the risk of sexual dysfunction?

Over 2million children die each year of pneumonia, many in Sub-Saharan Africa. What health maintenance strategy for sickle cell disease prevents pneumonia in children less than five years of age if given compliantly?

PS is a 52 yo female status post total hysterectomy and double oophorectomy. She has no significant cardiovascular medical history, and her only medication is gemfibrozil (Lopid) 600mg bid for hypertriglyceridemia. She comes to the clinic with complaints of night sweats, hot flashes every 20 minutes, and vaginal irritation with sexual intercourse. Which is the BEST menopausal hormone therapy option?

Dabigatran is indicated in nonvalvular atrial fibrillation, venous thromboembolism, and VTE prophylaxis. If it needs to be reversed, the appropriate agent is:

A 55-year-old female with a history of chronic kidney disease presents with fatigue and pallor. Her hemoglobin is 9.0 g/dL, and her serum ferritin is 10 ng/mL. She weighs 60 kg. The patient is currently on a regimen of darbepoetin 500 mcg SC every three weeks. The decision is made to initiate parenteral iron therapy. Which of the following is the most appropriate treatment plan for this patient?