Allopurinol is a prodrug that is metabolized to the more active form oxipurinol, which is an antagonist of xanthine oxidase.  It is used for the treatment of gout, and to prevent uric acid renal crystalopathy.  Assuming that a patient is found to have a creatinine clearance of 45ml/min, what allopurinol dosing regimen would you recommend? CLcr ml/min Allopurinol Dose > 80 300mg daily 60 – 80 200mg daily 20 – 59 100mg daily 10 – 19 50mg daily < 10 100mg every 2 days  

Use the following excerpt from the prescribing information to determine the time to steady state if dosing is chnaged from twice daily to three times daily dosing. The extent of bioavailability of levetiracetam is not affected by food. Levetiracetam is not significantly protein-bound (

If the concurrent administration of an oral drug with food was shown to INCREASE the bioavailability of the drug, you would expect with high confidence to also note … (Choose the ONE best answer)

Use the following excerpt from the prescribing information to determine what effect the ingestion of food with a levetiracetam dose will have on the Caverage. The extent of bioavailability of levetiracetam is not affected by food. Levetiracetam is not significantly protein-bound (

The two jovian planets most similar in size and mass are:

Read the article above. Choose the correct choice from the words in parentheses.  Write your answers in the blanks below. 1.  _______ 2. _______ 3.  _______ 4.  _______ 5.  _______ 6. _______ 7. _______

Write your answers for the above exercise in the blanks below. _______ 2.  _______ 3.  _______ 4.  _______ 5.  _______ 6.  _______ 7.  _______ 8.  _______

Read this magazine article and complete it with the correct answers. Write the letter of the best answer in the blank. Genetically modified foods, or GM foods, are another _______ (a. area / b. result / c. reason / d. solution) of food safety that is lively with debate. On the one hand, genetic modification can enhance the nutritional value and production of some kinds of food. For example, one type of _______ (a. genetically engineer rice / b. genetically engineered rice / c. genetic engineered rice / d. genetic engineer rice) that can help many people avoid vitamin B deficiency has received   _______ (a. few praise / b. many praise / c. much praise / d. few praises). On the other hand, there are problems with GM foods. For example, pollen from a _______ (a. scientific alteration / b. scientifically alteration / c. scientific altered / d. scientifically altered) strain of corn grown in the Midwestern United States killed many _______ (a. honey bees / b. honey bee / c. the honey bee / d. the honey bees), a fact that outraged  _______ (a. publics / b. public / c. the publics / d. the public).      Many people in the European Union are now demanding that  _______ (a. food label / b. food labels / c. foods label / d. foods labels) identify genetically modified ingredients. At the present time, however,  _______ (a. a many / b. great many / c. little / d. few) companies have done so. This is largely because GM food have a  _______ (a rather negative stigma / b. negative rather stigma / c. rather negatively stigma / d. negatively rather stigma), even though every GM product in  _______ (a. groceries store / b. grocery store / c. grocery stores / d. the grocery stores) has undergone thorough testing for quality and safety. Judy Arnett has studied GM food for two decades, and she believes the “GM food may be the greatest advancement in food safety since the invention of  _______ (a. a refrigerator / b. the refrigerator / c. some refrigerators / d. many refrigerators).”

Use the following excerpt from the prescribing information to determine what effect the ingestion of food with a levetiracetam dose will have on the Caverage. The extent of bioavailability of levetiracetam is not affected by food. Levetiracetam is not significantly protein-bound (

Read the article above. Complete the article using one of the pronouns and the correct form of the verb. Write your answers in the blanks below. 1. _______ 2.  _______ 3.  _______ 4.  _______ 5.  _______ 6. _______