A 55-year-old female with a history of deep vein thrombosis is prescribed an anticoagulant that enhances the effects of prostacyclin.  What is the expected outcome of this therapy?

A 5-year-old boy presents with spontaneous joint bleeding and easy bruising. Laboratory tests show prolonged activated partial thromboplastin time (aPTT) and low factor VIII levels.  What is the most likely diagnosis? 

An 80-year-old female with a history of recurrent infections is diagnosed with a late-stage cancer.   What role does immunosenescence play in her cancer progression? 

A patient with an infection has elevated levels of cytokines in their blood. What is the role of these cytokines in acute inflammation? 

Which of the following is a common cause of rotator cuff injuries in the shoulder? 

A patient with a tissue injury is being treated for acute inflammation. Which of the following best describes the sequence of events that occur during this process? 

A newborn presents with asymmetry in gluteal folds during a well-baby exam. The Ortolani maneuver elicits a palpable “clunk.” Which of the following is the most likely diagnosis? 

A 70-year-old female’s cells are found to have entered replicative senescence.  What is the significance of this state? 

A 50-year-old male presents with numbness and tingling in his ring and little fingers. He reports that his symptoms are worse when he leans on his elbow or bends his arm for extended periods. Physical examination reveals a positive Tinel’s sign at the elbow.  What is the most likely diagnosis? 

A patient is infected with a bacterial pathogen. Which cells present antigens to CD4 T cells to initiate an adaptive immune response?