(16 pts.)  Give a full curved-arrow pushing mechanism for the following reaction, indicate the Lewis and Bronsted acids/bases for all INTERMOLECULAR steps. You can ignore stereochemistry in this problem. To preview image: Click Here  

(22 pts.)  For the following reaction: a) Give a full curved-arrow pushing mechanism for formation of BOTH products and indicate the Lewis acid and base at each step (LA or LB) and whether they are also Bronsted acids and bases (BA or BB). Include all reasonable resonance contributors for any intermediates AND INDICATE THE MAJOR RESONANCE CONTRIBUTOR. To preview image: Click Here     b) Indicate which product, A or B,  is the one more likely to be formed under thermodynamically controlled conditions and which is more likely to be formed under kinetically controlled conditions.   c) Indicate which is most likley to be formed under conditions of high temperature, and give a BRIEF 1 sentance explanation.

(18 pts). Give the complete curved arrow pushing mechanism for the provided reaction showing formation of BOTH bromoalkane products Indicate the Lewis acid/Lewis base (LA, LB) at each step as appropriate, and whether they are also Brønsted acids/bases (LA/BA, LB,BB) To preview image: Click Here  

Calculate the growth rate of a bacterial culture that has a doubling time of 60 minutes. All formulas related to microbial growth kinetics discussed in class are shown below: 

Because they lack gut microbiota, germ-free pups undergoing hand-rearing can develop intestinal bleeding due to deficiency in which prevents clotting. 

Microbiota-associated factors that can impact colonization of the gut include:

Two participants in a study show much greater microbiome differences between each other than across repeated samples from the same person. Which implication does high inter-individual variability have for study design?

Sample derivatization is used in metabolomics to increase the volatility and stability of certain metabolites during analysis. 

Which microbial group is most likely to require complex or habitat-simulating media for successful cultivation?

A client is newly diagnosed with bipolar manic episodes. What drug class and medication will most likely be prescribed for the client?