Which of the following is true about the expression of RAG-1 and RAG-2 genes?

Centroblasts are found in the dark zone of germinal centers and centrocytes in the light zone of germinal centers.

Which of the following correctly describes promiscuous binding?

You would expect the Igα and Igβ genes to be turned off (not expressed) during which stage/s?

MHC Class I presents ____ antigens to ____ T-cells.

Centroblasts are found in the dark zone of germinal centers and centrocytes in the light zone of germinal centers.

TCR diversity is established as a result of:

Receptor editing involves successive rearrangement at the light-chain loci when reactivity to cell surface repetitive self-antigens occurs during B-cell development.

What chemokine specifically attracts B cells to the primary follicle?

Imagine you are a doctor and you discover your infant patient has a missense mutation of the RAG proteins which leads to partial enzymatic activity of RAG enzymes which leads to symptoms that show as autoimmunity.  Based on what we have discussed in class, you conclude that: