Which of the following receptor genes are the first to be rearranged in a double negative thymocyte?
Positive selection:
Positive selection:
Before positive selection, T cells can express two different…
Before positive selection, T cells can express two different ___ chains and therefore can express two different TCR’s on their surface.
Which of the following is the least common known lineage of…
Which of the following is the least common known lineage of the T-cells?
What does “double negative” thymocyte refer to?
What does “double negative” thymocyte refer to?
Which CDR’s in a TCR recognize and contact primarily the MHC…
Which CDR’s in a TCR recognize and contact primarily the MHC helices?
Both B-cells and T-cells have up to 4 potential attempts to…
Both B-cells and T-cells have up to 4 potential attempts to productively rearrange their heavy chain and β-chain genes respectively.
Which of the following thymocytes could express two α chains…
Which of the following thymocytes could express two α chains?
Effector T cell homing to inflamed tissue is facilitated by…
Effector T cell homing to inflamed tissue is facilitated by _________ expression on the effector T cell surface.
Allelic exclusion at the α chain locus is tightly regulated…
Allelic exclusion at the α chain locus is tightly regulated and very rarely will a T-cell express a second α chain.