A mouse line in Dr. Tolentino’s laboratory has acquired a no…
A mouse line in Dr. Tolentino’s laboratory has acquired a novel mutation impacting receptor-mediated endocytosis. When Dr. Tolentino examines the mouse cells under a microscope, she observes that coated pits and coated vesicles are forming, but they are accumulating at the plasma membrane and none are appearing in the cell cytosol, suggesting they they are not pinching off the cell surface. What protein do you suspect the novel mutation has occurred in?