A 40-year-old female patient has increased thyroid-stimulati…
A 40-year-old female patient has increased thyroid-stimulating hormone (TSH) and decreased T4 levels with a normal T3 level. Antithyroglobulin is measured as 1:1,280, and the antimicrosomal level is reportedly 1:6,400. This disease is characterized by hypoactivity of the thyroid with weight gain and a sluggish metabolism as a result of destruction of thyroglobulin. This patient most likely has: