A 45-year-old man presents to the clinic with symptoms of ma…
A 45-year-old man presents to the clinic with symptoms of major depressive disorder (MDD) that have progressively worsened over the past few months. He reports experiencing deep sadness, significant weight loss, early morning awakening, and a marked lack of interest in activities he used to enjoy. He describes his mood as distinctly worse in the morning, and notes that even positive events fail to lift his spirits. Physical activity seems more difficult, and he struggles with feelings of worthlessness. Given the patient’s presentation and history, what is the most likely subtype of MDD that he is experiencing?