Suppose a team of researchers investigated the association b…
Suppose a team of researchers investigated the association between obesity and gallstones using a prospective cohort study design. The researchers were concerned about confounding by high cholesterol diet, so they performed a few different analyses in which they attempted to minimize confounding. The results of their analyses are reported in Table 1. Table 1. Unadjusted, stratified, and Mantel-Haenszel effect estimates from the hypothetical study on obesity and gallstones. Unadjusted Estimates Estimates for the subsample with a low cholesterol diet Estimates for the subsample with a high cholesterol diet Mantel-Haenszel estimates Odds ratio 3.24 3.01 2.83 2.92 Risk difference 0.20 0.17 0.17 0.17 Based on the information in Table 1 report the following information: Was it appropriate to estimate an odds ratio using Mantel-Haenszel methods (yes/no)? (2 points) Explain why this is/is not appropriate (2 points). Was it appropriate to estimate a risk difference using Mantel-Haenszel methods (yes/no)? (2 points) Explain why this is/is not appropriate (2 points).