Glycine is acetic acid (ethanoic acid) with an amine group a…
Glycine is acetic acid (ethanoic acid) with an amine group attached i.e. 2-amino acetic acid. The pKa of the glycine carboxyl group is 2.34 and the pKa of acetic acid is 4.75. Briefly explain why there is such a large difference in the pKa values between these two carboxylic acid groups.