BCH4024 OC Sp25 E2 Q41: Common genetic causes of severe adul…
BCH4024 OC Sp25 E2 Q41: Common genetic causes of severe adult obesity are loss-of-function mutations in the melanocortin signaling pathway. One effect of these mutations is aberrantly low levels of activated protein kinase A (PKA) in certain cells of the hypothalamus. What type of mutation would most likely produce low levels of activated PKA?