Duarte – Transplantation Immunology In kidney transplantatio…
Duarte – Transplantation Immunology In kidney transplantation, a significant effort is put into reducing organ ischemia times and matching between donors and recipients, prior to transplantation. (A) Briefly define the three key stages involved in the matching process when identifying a suitable donor kidney for a transplant recipient, and what specific immune responses or incompatibilities the transplant team aims to avoid with each stage. (6 points) (B) Briefly define one main aspect of how ischemia-reperfusion injury activates the innate immune response and how it contributes to the activation of the recipient’s adaptive immune response and the development of graft rejection. (2 points)