Human serum albumin has many natural genetic variants, but m…
Human serum albumin has many natural genetic variants, but most are rare. Their frequency differs by population; some detectable forms (like bisalbuminemia or certain named variants) appear roughly between about 1 in 1,000 to 1 in 3,000 people in some groups. These variants usually don’t cause disease, but they can slightly change how albumin binds molecules and are useful for studying human populations and protein function. The figure below is taken from a paper titled “Chain Length-dependent Binding of Fatty Acid Anions to Human Serum Albumin Studied by Site-directed Mutagenesis”, published in 2006 in the Journal of Molecular Biology. Considering this, choose all of the following statements that are correct.