A 48-year-old man with a 30–pack-year smoking history presen…
A 48-year-old man with a 30–pack-year smoking history presents for help with quitting. He has no history of depression, seizures, or cardiovascular disease. He has attempted to quit twice in the past using willpower alone but relapsed within weeks due to strong cravings. He expresses high motivation to stop now, stating, “I’ll try whatever works best.” Which first-line pharmacologic intervention is most appropriate to recommend?