Ceftriaxone is eliminated exclusively via hepatic and renal…
Ceftriaxone is eliminated exclusively via hepatic and renal pathways and exhibits a total clearance of 42 L/h. Following intravenous administration, 67% of the administered dose is recovered in urine as unchanged drug, while 11% is recovered as metabolites. Based on this information, the biliary clearance of ceftriaxone is: