The IFN-gamma made by the cells above then bind to cytokine…
The IFN-gamma made by the cells above then bind to cytokine receptors on virus-infected cells and activate JAK/STAT signaling to induce their antiviral effects. You perform a Western blot for the phosphorylation status of JAK on virus-infected cells incubated with the IFN-gamma made from “A” cells and the “B” cells from the experiment from the previous question above. Will JAK be phosphorylated in “A” cells? How about “B” cells? Explain your reasoning.