For the last portion of the exam you need to answer 3 and on…
For the last portion of the exam you need to answer 3 and only 3 questions from the following list, each one worth 5-points. You are provided three response boxes after the list. Answer a single question per box, and refer to the question you are answering by its number in each box since copy-paste is disabled. For example: “1. here is an awesome answer that is correct!” The list: Why are primary brain tumors usually astrocytic in character? “Taste is not biochemically uniform.” What is meant by this statement? Provide at least two examples demonstrating this point. Imagine three neurons: two inputs converging on a single target. One input is glutamatergic, the other is GABAergic. If both inputs fire at the same time, thus communicating with the target, which input signal is favored (“wins”) to influence the target? Why? How does LTP work? LTP has mostly been studied in the hippocampus, why is this challenging as a mechanism for memory? What roles do natural killer cells and CD8+ T cells play in the immune system? How are they different? Why is antibody generation typically the end goal for considering a vaccine successful? Why is age the most tightly correlated factor for incidence when considering all cancers? There is substantial variability among expressed BCR, TCR, and both MHCs. Why is this variability important? How is the genetic mechanism of variation different for the antigen receptors versus the MHCs? What mechanisms/processes are instituted in the development and activation schemes of T cells and B cells that allow tolerance of self (and thus prevent autoimmunity)?