During embryonic development in a mammalian model, a mutatio…
During embryonic development in a mammalian model, a mutation completely knocks out the function of the transcription factor SOX9. However, the embryo’s karyotype is normal (46,XY), and its SRY gene on the Y chromosome is perfectly intact and actively transcribed. What will be the developmental fate of this embryo’s indifferent bipotential gonads?