A 15-year-old with sickle cell disease reports chest tightne…
A 15-year-old with sickle cell disease reports chest tightness and fatigue after an infection. On exam, the doctor notes symptoms worsen when oxygen levels drop. A. Explain how altered hemoglobin is produced from genetic information in eukaryotic cells.B. Explain why a substitution mutation can change protein behavior under low-oxygen conditions.C. Predict one downstream effect on tissue function or metabolism that would be expected during low oxygen states.