A 43-year-old woman presents with for evaluation of unintend…
A 43-year-old woman presents with for evaluation of unintended weight gain of nearly 10.3 kg (22lb) over the past year. Her blood pressure is 160/100 mmHg, height 160 cm (5’3”) and weight 77 kg (170 lb). On physical examination, her face is round and flushed, and her weight is concentrated around her abdomen. Her arms and legs are comparatively thinner. Findings of her breast and pelvic examinations are unremarkable, except for thick, reddish-purple streaks around her breasts. Laboratory findings show an abnormal overnight dexamethasone suppression test and high 24-hour urine-free cortisol. Her adrenocorticotropic hormone (ACTH) level is 3 pg/mL (Reference value >10 pg/mL). Which of the following is the most likely diagnosis?