A 67-year-old man has had progressive dyspnea for the past 2…
A 67-year-old man has had progressive dyspnea for the past 2 years with cough productive of small amounts of white sputum on most days of the week. The cough and shortness of breath sometimes awaken him from sleep. His past medical history is significant for hypertension and glaucoma. He has a 40 pack-year history of smoking and drinks 1-2 beers on weekends. Physical examination reveals prolonged expiration, wheezes and rhonchi over both lung fields. No peripheral edema is noted. Chest radiograph shows hyperinflation. Which of the following is the most likely diagnosis?