A 68-year-old male with a history of acute myeloid leukemia…
A 68-year-old male with a history of acute myeloid leukemia is admitted to the ICU with complaints of shortness of breath and acute hypoxic respiratory failure requiring continuous BiPAP. His vital signs show a temperature of 101.6, a HR of 104, a RR of 29, A BP of 134/78 mmHg, and an O2 saturation of 86% on 2L NC for which he was changed to BiPAP. CXR shows evidence of diffuse alveolar infiltrates bilaterally. His CBC reveals a WBC count of 103000/mcL. Shortly after being admitted to the ICU on continuous BiPAP the pt develops altered mental status and has to be restrained for trying to remove his BiPAP mask. A diagnosis of leukostasis is empirically made. Which of the following would NOT be an appropriate therapy for this patient?