A. In the following simplified diagram of the NFκB-dependent…
A. In the following simplified diagram of the NFκB-dependent signaling pathway, indicate which boxes (A to C) correspond to the NF-κB, IκB, and IKK proteins, respectively. B. You add okadaic acid, a chemical that removes phosphate groups from proteins, to cells that have activated NF-κB signaling in response to IL-1. How will okadaic acid affect NF-κB signaling? Explain your reasoning. In your explanation, make sure to describe the functions of the NF-κB, IκB, and IKK proteins and how they lead to expression of inflammatory response genes in response to the IL-1 signal and how this will be affected by okadaic acid.