A woman has a son with Fragile X syndrome. Parental testing…
A woman has a son with Fragile X syndrome. Parental testing of the mother shows that she has one allele with a repeat of 90 (the risk of expansion to a full mutation is 80%). She is now pregnant with a girl. What is the chance that the daughter would have premature ovarian insufficiency (POI) as an adult (the chance of developing POI is 20% in women with FMR1-related premutations)?