Blanks #1 through #5: Complete hydrolysis of the lipid below…
Blanks #1 through #5: Complete hydrolysis of the lipid below gives which five molecules? List one molecule per blank. Describe specific fatty acids by their delta nomenclature (e.g. 18:2 delta 4, 7 fatty acid). Blank #6: The unsaturated fatty acid is an omega fatty acid Blank #7: Is this lipid likely to be part of the inner or outer leaflet of the plasma membrane? In response to certain hormonal signals, phospholipase A2 hydrolyzes the unsaturated fatty acid (arachidonic acid) from the lipid above. Arachidonic acid then serves as a precursor to various eicosanoids. These include prostaglandins (such as PGE2, PGI2), thromboxane A2 (TXA2), and leukotriene A (see the diagram below). Blank #8: Non-steroidal anti-inflammatories (NSAID’s) such as aspirin or ibuprofen reduce pain and inflammation, cause bleeding, but have no effect on smooth muscle contraction. Explain this statement by describing how NSAID’s impact the formation of various molecules in the diagram above.