BCH4024 OC Sp25 E2 Q28: Promising drugs have been developed…

BCH4024 OC Sp25 E2 Q28: Promising drugs have been developed to treat invasive cancers. A class of these drugs act as competitive inhibitors of ATP binding to active sites of receptor tyrosine kinases (RTKs). What are some possible downstream effects of RTK activation in healthy cells?

BCH4024 OC Sp25 E2 Q41: Common genetic causes of severe adul…

BCH4024 OC Sp25 E2 Q41: Common genetic causes of severe adult obesity are loss-of-function mutations in the melanocortin signaling pathway. One effect of these mutations is aberrantly low levels of activated protein kinase A (PKA) in certain cells of the hypothalamus. What type of mutation would most likely produce low levels of activated PKA?