A 35-year-old male visits his physician with complaints of f…

A 35-year-old male visits his physician with complaints of fatigue and weakness, and loss of appetite. Upon physical examination, the physician finds that the patient’s spleen is enlarged. The patient reports no history of blunt contact to the abdomen that would cause such enlargement. The most striking lab results are anemia, leukopenia, and thrombocytopenia. The results also indicate that lymphocytes with abnormal morphology demonstrating cytoplasmic projections are within the peripheral blood. Which marker is highly specific for this leukemia?

A 9-month-old boy is suspected of having an immune deficienc…

A 9-month-old boy is suspected of having an immune deficiency because he had many recurrent infections with Streptococcus pneumoniae. Laboratory tests reveal a normal percentage of T cells and T-cell subsets but a lack of mature B cells and immunoglobulins. This boy most likely has: