An investigator conducts a study comparing lowopril (a new A…

An investigator conducts a study comparing lowopril (a new ACE-inhibitor) to lisinopril in patients with uncontrolled hypertension. The NI margin is set at 6 mmHg. Lowopril lowered blood pressure by 6.1 mmHg and lisinopril lowered by 7.8 mmHg. The difference in blood pressure lowering was 1.7 mmHg (95%CI -0.1 to 3.5). Describe the appropriate interpretation of the results in the context of the NI margin.

A new antihistamine, metalazine, is compared to placebo for…

A new antihistamine, metalazine, is compared to placebo for mild-to-moderate seasonal allergies. An allergy symptom visual analog scale of 0, meaning no symptoms, to 10, meaning the worst symptoms imaginable is used as the primary outcome. Metalazine was found to decrease the allergy symptoms visual analog scale by 3.2 points (95%CI -0.4 to 7.8). Which of the following statements best describes the potential type of statistical error present in this study?