A 73 year female patient presents with anemia and thrombocyt…

A 73 year female patient presents with anemia and thrombocytopenia. On her peripheral smear, the tech notes the presence of marked aniso/poikilocytosis, RBC’s with Howell Jolly bodies, oval macrocytes, hyposegmentation of some neutrophils. The patient’s Vitamin B12 and folate levels are within normal range. Possible diagnosis may be: