The human blood group glycophorin molecules are heavily glycosylated and  carry the vast majority of which  membrane-associated carbohydrate? (M2.2)

A donor genotypes as group O but shows weak reactivity with anti-A and strong reactivity with Helix pomatia lectin. Dolichos biflorus is negative. What antigen is likely present? (M2.1) 

Which antigen is defined by L-fucose α1→2 galactose? (M1.1)

A patient with Fy(a–b–) of African ancestry does not produce anti-Fyb. Why? (M1.3)

A patient with prior anti-Jka history presents with anemia after transfusion. Current antibody screen is negative. What explains this? (M1.4)

Clinical History: A 32-year-old woman of Polynesian ancestry is evaluated as a blood donor. Her RBCs resist lysis in 2M urea. She has no history of transfusion or pregnancy. Question: Which molecular finding is most consistent with her phenotype? (M2.4)

Clinical History: A 45-year-old man of African ancestry with sickle cell disease presents with a delayed hemolytic transfusion reaction. Antibody screen reveals anti-Fy3. RBC phenotype is Fy(a–b–).  Question: What does the presence of anti-Fy3 suggest about this patient’s genotype? (M1.3)

A patient develops anti-Vel. Which risk is greatest? (M2.3)

Clinical History: A 29-year-old pregnant woman is found to have anti-K antibodies at 24 weeks gestation. The fetus shows signs of anemia, but amniotic fluid bilirubin is low and reticulocyte count is suppressed.  Question: What is the most likely mechanism of fetal anemia in this case? (M1.2)

A Polynesian donor’s RBCs resist lysis in 2M urea. Which allele explains this? (M2.4)