Inhibition of the vascular endothelial growth factor (VEGF) receptor would have the highest impact on which of the following “Hallmarks of Cancer”?
Most standard chemotherapy drugs inhibit DNA replication and…
Most standard chemotherapy drugs inhibit DNA replication and therefore target which of the following cell cycle phases in cancer cells?
Due to regions of mismatch, miRNAs only target a single mRNA…
Due to regions of mismatch, miRNAs only target a single mRNA rather than multiple mRNAs in a network
Canine parvovirus kills cardiac myocytes by causing cell lys…
Canine parvovirus kills cardiac myocytes by causing cell lysis when it exits the cell
Poisonous animals are those which produce substances that ar…
Poisonous animals are those which produce substances that are toxic when injected
In the failing heart, ATP production is less efficient leadi…
In the failing heart, ATP production is less efficient leading to an energy deficit
In the normal heart, 90% of the ATP needed is produced throu…
In the normal heart, 90% of the ATP needed is produced through which of the following metabolic processes?
miRNAs primarily target mRNAs by inhibiting mRNA translation…
miRNAs primarily target mRNAs by inhibiting mRNA translation (rather than cleavage)
Which of the following is one of the main energy demands in…
Which of the following is one of the main energy demands in the normal adult heart?
In heart failure, increased activity of Class-I histone deac…
In heart failure, increased activity of Class-I histone deacetylases (HDACs) decreases expression genes that are involved in which of the following processes?