Your company has hired you to analyze different vascular graft surfaces. A. (1 pts) In your first experiment, you’ve quantified the number of adhered platelets on the different vascular graft surfaces (ePTFE, POC, and POC with heparin incorporated) after a parallel flow chamber assay. Based on the plot below, which surface(s) would be best and which would be worst for a vascular graft? Briefly describe your rationale (2 sentences or less) B. (.5 pts) Do you think outside-in or inside-out integrin activation is likely for your grafts? Briefly (2 sentences or less) describe why. C. (.25 pts) You’re interested in determining which integrin receptor is responsible for platelet adhesion to your vascular grafts for your ePTFE and POC grafts. You’ve found there is an increase in Integrin α11/β1 for both. Which type or integrin receptor is involved based on the graphical representation below?    D. (.5 pts) Being a biomedical engineer, you also know that it is very important for your endothelial cells to retain their elastic properties when exposed to a vascular graft. You’ve performed Real-time PCR and quantified Elastin expression in endothelial cells cultured on your grafts after 3 days (ePTFe = orange, POC = green, POC-heparin = blue). You’ve also included the red as a control – is your red a positive or negative control? Provide your rationale – consider if it has higher or lower Elastin expression than your experimental groups. E. (.5 pts) What does real-time PCR quantify (1 sentence or less)?

Use the Law of Exponents to rewrite and simplify the expression. ​ ​

Find an expression for the area under the graph of f as a limit. Do not evaluate the limit. ​

Suppose that , , , and . Find the value of . ​

Your company has hired you to analyze different vascular graft surfaces. A. (1 pts) In your first experiment, you’ve quantified the number of adhered platelets on the different vascular graft surfaces (ePTFE, POC, and POC with heparin incorporated) after a parallel flow chamber assay. Based on the plot below, which surface(s) would be best and which would be worst for a vascular graft? Briefly describe your rationale (2 sentences or less) B. (.5 pts) Do you think outside-in or inside-out integrin activation is likely for your grafts? Briefly (2 sentences or less) describe why. C. (.25 pts) You’re interested in determining which integrin receptor is responsible for platelet adhesion to your vascular grafts for your ePTFE and POC grafts. You’ve found there is an increase in Integrin α11/β1 for both. Which type or integrin receptor is involved based on the graphical representation below?    D. (.5 pts) Being a biomedical engineer, you also know that it is very important for your endothelial cells to retain their elastic properties when exposed to a vascular graft. You’ve performed Real-time PCR and quantified Elastin expression in endothelial cells cultured on your grafts after 3 days (ePTFe = orange, POC = green, POC-heparin = blue). You’ve also included the red as a control – is your red a positive or negative control? Provide your rationale – consider if it has higher or lower Elastin expression than your experimental groups. E. (.5 pts) What does real-time PCR quantify (1 sentence or less)?

Use the Law of Exponents to rewrite and simplify the expression. ​ ​

Find an expression for the area under the graph of f as a limit. Do not evaluate the limit. ​

Find the number c that satisfies the conclusion of the Mean Value Theorem on the given interval. ​ ,  ​

Take a moment to show your handwritten formula/notes sheet to the camera (show front and back).  Now do a full room scan of your testing environment. You SHOULD have done this already, but Honorlock had some issues in Exam 1, so we’re repeating this step manually. You should do a 360 of your testing environment. Make sure any secondary monitors are turned off. You should both above and below your work surface including any external devices should be out of reach. Your final camera angle should include your face and your entire work area including your scratch paper and your formula sheet.  Now number your other pages for scratch work with the page number circled on the upper left of each page front and back. You can have up to 10 sheets of paper, so put 1 on the first side and 2 on the back side for up to a total of 10 sheets of paper and 20 sheets. Show each blank page front and back to the Honorlock video camera monitor.  When you are completing different problems, write the problem number and then draw a square around the problem number so that we can easily tell the difference between page number and problem number in your scanned results.  Please write “I understand that I am bound by the ASU honor code and will not use any unallowable outside resources” at the top of the page 1 and then sign and date your name. 

Leader-member exchange theory focuses on the leader’s