Which of the following is NOT considered a barrier to the diffusion of certain chemicals in the blood based on specializations of the blood vessels and other factors?

The physiologically based model of disposition is more complex than the one or two compartment models.

Biotransformation has the ability to produce a metabolite that is more toxic than the parent compound.

Toxicants bound to plasma proteins are more prone to cross cell membranes because they are more likely to be recognized by the cell.

Mercury bioaccumulates in the food chain.

Which of the following is NOT a specific aspect of disposition that is of primary importance?

Heavy metals typically reside in bone for decades.

The persistence of DDT in the body is related to its lipophilic nature.

Which exposure pathway has the fastest uptake in the human body?

A fish is exposed to a water environment that has concentration of 100ug/L of toxicant A for 2 months. After that time period, the fish is sacrificed and found to have a calculated BCF of 0.5. This indicates _____.