A 20-year-old male is seen by his physician following a week…

A 20-year-old male is seen by his physician following a weekend backpacking trip to the mountains.  His CBC reveals a peripheral blood morphology including hypochromia, anisocytosis, and poikilocytosis.  Cellulose acetate hemoglobin electrophoresis yields Hgb A = 47%, Hgb S = 50%, Hgb A2 = 3%.  These results are consistent with which of the following:

The following results are obtained on sample run during a ro…

The following results are obtained on sample run during a routine doctor’s visit. WBC 152.0 NEU% 9.21 LYM% 85.6 MONO% 1.21 EOS% .008 BASO% 3.96 RBC 2.20 HGB 7.18 HCG 20.5 MCV 93.4 MCH 32.6 MCHC 34.9 RDW 15.3 PLT 212 MPV 10.4                                          Suspect Population Flags: Variant Lymphocytes, Fragile WBC What is the most likely diagnosis?

A 65-year old male is seen by his physician for splenomegaly…

A 65-year old male is seen by his physician for splenomegaly, abdominal discomfort, mild lymphadenopathy, and recurrent infections.  Peripheral blood reveals a pancytopenia with large lymphocytes that have an oval to kidney-shaped nucleus.  The cytoplasm is pale blue with poorly defined borders and appear to have threadlike projections.  These cells were tested using flow cytometry and found to be positive for CD19, CD20, and CD21.  The cells were found to be acid phosphatase positive.  The color of the stain remained after the addition of L-tartrate.  These results are most indicative of which of the following?