To move quickly, a breed of domesticated rabbit called saute…

To move quickly, a breed of domesticated rabbit called sauteur d’Alfort sends its back legs sky high and walks on its front paws. That strange gait (handstand gait) may be the result of a gene called RORB, which is tied to limb movement.   (you do not have to watch the six second video to answer the question)   Imagine the pedigree below belongs to a family of rabbits where some members have the handstand gait.  Based on this pedigree, what is the best conclusion regarding the mode of inheritance of this trait? What is the genotype of individual II-8? If II-5 and II-6 had bunnies, what would be their phenotype?     M. Carneiro et al. A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits. PLOS Genetics. Published online March 25, 2021. doi: 10.1371/journal.pgen.1009429.   

You are studying mice that are obese due to a mutation in th…

You are studying mice that are obese due to a mutation in the gene encoding the leptin receptor.  The obese phenotype is an autosomal recessive condition.    Which of the following statements is ACCURATE regarding obese mice with a defect in the leptin receptor?