You are consulting Peds Neurology for a 6 week old patient w…

You are consulting Peds Neurology for a 6 week old patient who presented to the pediatric floor with severe hypotonia and poor feeding. His birth history reveals an uncomplicated pregnancy and normal birth. His birth weight was 2500 g at 39 weeks GA. His APGAR scores were 8 and 9. On exam, he has a wide nasal bridge, low set ears, upturned nose, micrognathia, and a sacral dimple. Neuro exam reveals severe hypotonia with normal spontaneous movements and deep tendon reflexes. The metabolic newborn screen was normal. The head ultrasound shows a smooth cortex with mild ventriculomegaly. Which is the most appropriate next test in order to make the most appropriate diagnosis?

A 13-year-old male presents with a 24-hour history of sharp,…

A 13-year-old male presents with a 24-hour history of sharp, pleuritic chest pain that is worse in the supine position. He recently had a viral illness a few weeks ago. Now has a fever at 38.5 C and a pericardial friction rub is heard on exam. The most likely diagnosis is: