A patient presents with a bacterial infection, and their innate immune response is activated. Which of the following cells is most likely to be rapidly recruited to the site of infection? 

A 70-year-old male with a history of chronic inflammatory conditions presents with new-onset fatigue and weight loss. Laboratory tests reveal elevated inflammatory markers and abnormal white blood cell counts.  What is the most likely explanation for his increased cancer risk? 

What is the impact of immunosenescence on cancer risk in older adults? 

A 35-year-old female is diagnosed with melanoma. Genetic testing reveals a gain-of-function mutation in the BRAF gene, a proto-oncogene.  What is the primary consequence of this mutation? 

Where do B cells develop and mature? 

How can cancer-causing viruses contribute to cancer development? 

A patient with a bacterial infection has elevated levels of mannose-binding lectin. Which pathway of the complement system is likely activated in this patient? 

A 40-year-old male is diagnosed with Li-Fraumeni syndrome, a hereditary cancer syndrome associated with mutations in the TP53 gene.  What is the primary function of the TP53 gene in normal cells? 

A 30-year-old male athlete experiences increased bone density in his lower limbs after a period of intense training.  Which cells are primarily responsible for this adaptive response? 

A 45-year-old male with a history of osteoporosis is found to have low bone density on a DEXA scan. Laboratory tests show normal calcium and phosphate levels.  What is the most likely explanation for his low bone density?