AS: A 60-year-old female presents with persistent swelling i…

AS: A 60-year-old female presents with persistent swelling in her legs, which has been gradually worsening over the past few months. She reports no pain, but the swelling increases by the end of the day. The patient has a history of breast cancer treated with surgery and radiation therapy. Lymphoscintigraphy reveals decreased lymphatic drainage in the lower extremities, and a Doppler ultrasound rules out deep vein thrombosis. What is the most likely diagnosis?

EM: A 25-year-old male visits the doctor after experiencing…

EM: A 25-year-old male visits the doctor after experiencing a persistent fever, fatigue, and excessive sweating while sleeping. The patient has lost over 35 pounds since his last annual visit 8 months ago without attempting to lose weight. During the physical, the doctor discovers swelling in the lymph nodes around his armpits and neck. The doctor orders a blood test and when observing a sample under the microscope, identifies Reed-Sternberg cells present in the patient’s blood. What do these cells signify?