I don’t know what does that word mean.

The conjugate acid OH- of  is ________.

A typically has a personality type that avoids conflict.  

(4 pts) Which would you expect to be higher, the RWork or RFree of a crystal structure? Why? 

(9 pts) Describe the steps required for determining the structure of a small protein domain by solution-state NMR, providing experimental details on the preparation of samples as well the type of spectra that need to be recorded. It’s not essential to provide the exact name of each NMR experiment but to describe the information obtained by each experiment. 

(6 pts) Name three key technical advances that enabled routine high-resolution cryo-EM structure determination. For each, briefly describe how it improved data quality or resolution.

(4 pts) Protein crystals are ordered arrays of protein molecules in three dimensions. Space group describes the symmetry of the crystal lattice. Explain the reason why only 65 space groups are possible for protein crystals, in comparison to a total of 230 observed for inorganic or organic small molecules. 

(3 pts) What does the B-factor measure? 

79Ft with chronic cancer-related pain is receiving fentanyl 50 mcg IV every 2 hours PRN for severe pain. Due to a change in clinical status, the provider decides to switch to IV hydromorphone. Using equianalgesic dosing, what is the most correct dose of hydromorphone? IV fentanyl 100 mcg ≈ IV morphine 10 mg  

A patient has been taking the monoamine oxidase inhibitor (MAOI) phenelzine (Nardil) for 6 months. The patient wants to go to a party and asks the RN, “Will just one beer be a problem?” Which advice from the nurse is correct?