Match the cellular biology to the responsible gene.

A 57‑year‑old woman with obesity, pre‑diabetes, and a strong family history of breast and colon cancer begins a structured exercise program after counseling in your clinic. She now performs brisk walking 40 minutes/day, 5 days/week, plus resistance training twice weekly.  Which of the following are cellular effects of this type of regular exercise? (SELECT ALL)

A 36‑year‑old woman is undergoing evaluation for a rapidly growing ovarian tumor. Pathology shows that many tumor cells are stuck in metaphase with paired sister chromatids still attached, despite having normal spindle formation. Additional testing reveals a loss‑of‑function mutation affecting a ubiquitin‑ligase complex responsible for triggering chromatid separation and promoting mitotic exit. Which defect best explains the cell‑cycle abnormality seen in her tumor?

Match the physiological action to the appropriate growth factor or mitogen.

Match the presenting symptoms with the most likely related neoplasm.

Which germ layer do most pediatric cancers originate from? 

What is the primary role of caretaker genes in maintaining normal cellular function?

A context diagram:

Directions: The second map quiz is intended to assess your knowledge of the geographical features and locations related to Central and South America. The quiz will ask you to identify 25 countries or physical features in Central and South America.Time Limit: You will have 30 minutes to complete the map quiz. Time limits are placed on the map quizzes as it is the expectation that the students will know the material well enough to answer questions without the use of additional outside resources.Point Value: The map quiz is worth 50 points.Proctoring: As this map quiz is being administered using the Honorlock proctoring system, please make sure to enter the quiz through the Content tab. Attempting to enter the map quiz through the Blackboard calendar tool or Blackboard notifications will not allow you to access the quiz or not load properly. Students also should use Google Chrome when taking the map quiz as Google Chrome is compatible with the Honorlock system.Please note that this quiz is closed book and closed notes. I count on the honor code from each of you to ensure that no cheating is involved.Remember that you can take the quiz only ONCE. Therefore, please do not start taking the quiz until you are ready to do so. Once you open the quiz, you must complete the entire quiz. You will see all of the quiz at once, so make sure to scroll all the way down the page to complete the entire quiz.

If a child has not been on antibiotics for the past month and has no known drug allergies, which of the following is recommended as first-line treatment for acute otitis media?